主持的代表性科研项目

1 2023.07-2024.07 中国石油集团科学技术研究院有限公司开放基金资助课题, 2023-KFKT-20 ,耐温抗盐生物聚合物产生菌筛选与发酵工艺研究,主持;

2 2020.01-2022.12 国家自然科学基金青年项目, 3190050, 鞘氨醇单胞菌 NXdG 微氧高效合成胞外多糖的机制及其应用研究,主持;

3 2020.11-2024.10 国家重点研发计划, 2020YFC1808620, 子课题 场地表层低成本、强富集复合净化材料的可控制备与示范验证 ,子课题参与单位负责人;

4 2018.11-2022.07 中国博士后科学基金面上资助, 2018M641629 ,原位构建温敏双向开关调节黄原胶流变学特性研究,主持;

5 2016.09-2018.08 中国博士后科学基金面上资助, 2016M601251 ,利用基因工程技术提高黄原胶的热稳定性研究,主持

6. 2019.05-2020.05 南开大学 2019 年度基本科研业务,不同结构黄原胶变体的原位定制及其应用分析,主持;

代表性学术论文

1. Shi, Z., Ming, Y., Li, J., Lin, Y., Wang, W., Sha, W., Li, G*., Wu, M *., & Ma, T*. (2026). Engineering compartmentalized utilization of glycerol with glucose for high-level chondroitin production in Corynebacterium glutamicum . Carbohydrate polymers , 378 , 124946. ( 通讯作者,一区 )

2 Shi Z, Ming Y, Li J, Zhao Y, Wang W, Sha W, Li G*, Wu M *, Ma T*,Production of chondroitin by Corynebacterium glutamicum through co-utilization of glucose and xylose from corn straw, International Journal of Biological Macromolecules, 2025,327,147392 ( 通讯作者,二区 )

3 Ming Y, Shi Z, Zhao Y, Li J, Sha W, Wang W, Li G*, Wu M *, Ma T* Preparation and characterization of microcapsules using an acid-tolerant sanxan gum combined with sodium alginate/chitosan and their application in Lactobacillus plantarum delivery. Carbohydrate Polymers, 2025, 123638. ( 通讯作者,一区 )

4 Wu M #, Shi Z#, Ming Y, Zhao Y, Gao G, Li G*, Ma T*. The production of ultrahigh molecular weight xanthan gum from a Sphingomonas chassis capable of co-utilizing glucose and xylose from corn straw. 2024, Microbial Biotechnology. ( 一作,二区 )

5 Ming Y, Li Guoqiang, Shi Zhuangzhuang, Zhao X, Zhao Y, Gao G, Ma T*, Wu M *. Co-utilization of glucose and xylose for the production of poly-β-hydroxybutyrate (PHB) by Sphingomonas sanxanigenens NX02. 2023. Microbial Cell Factories. ( 通讯作者,二区 )

6 Wu M , Shen Y, Ming Y, Shi Z, Li G*, T Ma*. Characterization of a polysaccharide hydrogel with high elasticity produced by a mutant strain Sphingomonas sanxanigenens NX03. 2022, Carbohydrate Polymers. 119030. ( 一作,一区 )

7 Wu M #, Shi Z#, Ming Y, Wang C, Qiu X, Li G*, Ma T*. Thermostable and rheological properties of natural and genetically engineered xanthan gums in different solutions at high temperature. International Journal of Biological Macromolecules. 2021, 182:1208-1217. ( 一作 , 一区 )

8 Wu M , Zhao X, Shen Y, Shi Z, Li G*, Ma T*. Efficient simultaneous utilization of glucose and xylose from corn straw by Sphingomonas sanxanigenens NX02 to produce microbial exopolysaccharide. Bioresource Technology. 2021 Jan;319:124126.( 一作 , 一区 )

9 Wu M , Qu J, Tian X, Zhao X, Shen Y, Shi Z, Chen P, Li G*, Ma T*. Tailor-made polysaccharides containing uniformly distributed repeating units based on the xanthan gum skeleton. International Journal of Biological Macromolecules. 2019 Jun 15;131:646-653. ( 一作 , 一区 )

10 Wu M , Qu J, Y Shen, Li G *, Ma T *. Gel properties of xanthan containing a single repeating unit with saturated pyruvate produced by an engineered Xanthomonas campestris CGMCC 15155. Food Hydrocolloids. 2018, 87:747-757. ( 一作 , 一区 )

11 Wu M #, Shi Z #, Tian X, Shen Y, Qu J, Dai X, Li G, Ma T *. Enhancement of transparent hydrogel sanxan production in Sphingomonas sanxanigenens NX02 via rational and random gene manipulation. Carbohydrate Polymers. 2018,189, 210-217. ( 一作,一区 )

代表性专利

1 、一种高酰基三赞胶及其生产菌株的分子标记和应用,天津市: CN113956372B (授权,技术转让)

2 、一种具有醇溶性和保湿性的天然三赞胶、免洗消毒凝胶和应用,天津市: CN114010533B (授权)

3 、一种天然合成的低酰基三赞胶及其生产方法和鉴定方法,天津市: CN114014944B (授权 , 技术转让)

4 、鞘氨醇单胞菌 T-3 及其共发酵生产生物多糖和聚 β 羟基丁酸的方法,天津市: ZL201510110078.3 (授权)

5 、一种具有高效合成 Wzy 型胞外多糖特性的鞘氨醇单胞菌株及其构建方法和应用,天津市: CN202111307643.7 (授权)

1 2020 年度中国轻工业联合会科学技术进步一等奖( 3/10 生物表面活性剂油藏原位发酵提高采收率关键技术研发与应用

2 2022 年度中国轻工业联合会科学技术进步一等奖( 4/10 黄原胶绿色智能制造及产业升级关键技术研发及应用

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