基本信息

招生专业

博士生（发酵工程）

硕士生（发酵工程）

专业学位硕士（生物工程、药学）

教育与工作经历

教育经历

1992~1996 齐齐哈尔轻工业学院 本科
1996～1999 大连轻工业学院 硕士
1999～2002 华南理工大学 博士

工作经历

2002～ 华南理工大学任教
2005年，晋升为副教授、研究生导师
2011年，晋升为教授。

教学与科研情况

教学：

本科生教学

担任《酶工程》、《发酵工程》的本科教学工作。

本科生导师制

研究生教学

《生化分离技术》研究生教学工作

教学成果（如果有，如教学奖项）

科研（科研兴趣）：

在科研方面，主要开展了以下工作：1）在生物催化与转化领域，重点进行了油脂酶法改性的非水相催化研究，解决了非均相体系非水相酶法转化技术的共性难题，建立起了较为完善的“油脂酶法改性”技术平台，在该平台基础上，针对油脂的酶法脱胶、甘油二酯、TG型PUFA、母乳化脂肪和环保增塑剂等项目开展了研究，多项技术成果实现产业化，部分项目技术达到国际先进水平，在国内外形成影响力。2）针对食品、医药、化妆品等领域的不同需求，进行新型脂质分子设计和进行生理功能评价，目前已针对M2结构脂、PUFA脂质家族等开展研究。3）为配合生物催化与转化的方面的研究，课题组还进行酶的分子克隆与改造、生物计算等方面的研究；课题组还采用活性微生物为工具，针对环保、饲料、农业、食品加工等领域的需求，筛选了多种功能微生物，开发出了系列微生物制剂，在企业进行了产业化转化，取得了良好的社会效益和经济效益。近年来，先后主持国家自然科学基金、863计划、广东省攻关、广州市攻关等20多项课题，指导研究生30多名，在JAOCS、Bioinformatics、J. Agric. Food Chem.等刊物上发表论文50多篇，申请专利20多件。

科研项目

代表性成果（论文、专利或软件著作权、成果转化等）

1. He SL ， Wang FH ， Ning ZX ， Yang B ， Wang YH. Autolysis of Anchovy(Engraulisjaponicus) Protein: Evaluation of Antioxidant Properties and Nutritional Quality of Resulting Hydrolysates. Journal of Aquatic Food Product Technology

2. Cao Y, Qi SJ, Zhang Y, Wang XN, Yang B, Wang YH. Synthesis of Structured Lipids by Lipase-Catalyzed Interesterification of Triacetin with Camellia Oil Methyl Esters and Preliminary Evaluation of their Plasma Lipid-Lowering Effect in Mice. Molecules 2013, 18, 3733-3744.

3. Wang FH, Guo SH, Liu YY, Lan DM, Yang B, Wang YH. Biochemical and conformational characterization of a leucineaminopeptidase from Geobacillusthermodenitrificans NG80-2. World J MicrobiolBiotechnol. 2012, 11:3227–3237.

4. Liu Lu, GaoChongliang, LanDongming, Yang Bo, Wang Yonghua, Molecular basis for substrate selectivity of a mono- and diacylglycerol lipase from Malasseziaglobosa, Biochemical and Biophysical Research Communications, 2012,424(2): 285-289.

5. Xu TT, Liu L, Hou SL, XuJX,Yang B, Wang YH, Liu JS. Crystal structure of mon- and diacylglycerol lipase from Malasseziaglobosareaveals a novel lid conformation and insight into the substrate specificity. Journal of Structure Biology, 2012, 178: 363-369.

6. Qin XL, Yang B, Huang HH, Wang YH. Lipase-catalyzed incorporation of different fatty acids into tripalmitin-enriched triacylglycerols: effect of reaction parameters. Journalof Agricultural and Food Chemistry, 2012, 60, 2377−2384

7. Wang FH,Ning ZX, Lan DM, Liu YY, Yang B, Wang YH. Biochemical Properties of Recombinant LeucineAminopeptidase II from Bacillus stearothermophilus and Potential Applications in the Hydrolysis of Chinese Anchovy (Engraulisjaponicus) Proteins. Journalof Agricultural and Food Chemistry , 2012, 60(1): 165-172

8. Wang WF,Li T,Ning ZX,Wang YH, Yang B,Ma YJ,Yang XQ. A process for the synthesis of PUFA-enriched triglycerides from high-acid crude fish oil. Journal of Food Engineering , 2012, 109: 366-371

9. Yang CF, Wang FH,Lan DM, Whiteley C, Yang B, Wang YH. Effects of organic solvents on activity and conformation of recombinant Candida antarcti ca lipase A produced by Pichiapastoris.Process Biochemistry, 2012, 47:533–537

10. Xu D, Sun LJ, Chen HY,Lan DM, Wang YH, Yang B. Enzymatic synthesis of diacylglycerolsenriched with conjugated linoleic acid by a novel lipase from Malasseziaglobosa . Journalof theAmerican Oil Chemist’s Society, 2012, 89: 1259-1266

11. Liu LP, Qin XL, Ning ZX, Wang YH, Yang B. Enzymatic synthesis of isopropyl ester by alcoholysis of camellia oil, Journal of the American Oil Chemists' Society ， 2012, 89: 1277-1285 . .

12. Lan DM,Tai Y,Shen YF, Wang FH,Yang B, Wang YH. Efficient purification of native recombinant proteins using proteases immobilized on cellulose. Journal of Bioscience and Bioengineering, 2012, 113:542-544

13. Wang WF,Li T,Qin XL,Ning ZX,Yang B,Wang YH. Production of lipase SMG1 and its application in synthesizing diacylglyecrol. Journal of Molecular Catalysis B-Enzymatic, 2012, 77:87–91

14. Zhu QS, Li T, Wang YH,Yang B,Ma YJ. A two-stage enzymatic process for synthesis of extremely pure high oleicglycerolmonooleate. Enzyme and Microbial Tech nology, 2011, 48:143-147.

15. Wang WF,Li T, Ning ZX, WangYH,Yang B, Yang XQ. Production of extremely pure diacylglycerol from soybean oil by lipase-catalyzedglycerolysis, Enzyme and Microbial Tech nology, 2011; 49: 192-196.

16. Shen YF, Wang FH, Lan DM, Liu YY, Yang B, Wang YH, Biochemical Properties and Potential Applications of Recombinant LeucineAminopeptidase from Bacillus kaustophilus CCRC 11223. International Journal of Molecular Science ， 2011, 12:7609-7625.

17. Lan DM, Hou SL,Yang N, WhiteleyC,YangB,Wang YH, Optimal Production and Biochemical Properties of a Lipase from Candida albicans . International Journal of Molecular Science, 2011, 12:7216-7237.

18. Lan DM,Yang N,Wang WK,Shen YF, Yang B, Wang YH. A Novel Cold-Active Lipase from Candida albicans : Cloning, Expression and Characterization of the Recombinant Enzyme, International Journal of Molecular Science, 2011 ， 12 ： 3950-3965.

19. Yang B,Wang WF, Zeng FK, Li T,Li Lin. Production and oxidative stability of a soybean oil containing conjugated linoleic acid produced by lipase catalysis. Journalof Food Biochemistry. 2011, 35:1612–1618

20. Zeng FK, Ning ZX, Wang YH, Yang B, Liu H, Application of enzymatic synthesized glycerol monooleate in the manufacture of low fat ice cream. Journal of Food Biochemistry, 2011, 116-121

21. LanDM,Wang WF,Sun LJ, Wang YH,Yang B. A novel vector for expression cloning of large numbers of polymerase chain reaction products in Pichiapastoris , African Jouralof Microbiology Research, 2011, 5:211-216

22. Lan DM, Yan HL, YangB,Wang YH. Blunt-end vectors generated by polymerase chainreaction (PCR) for direct cloning of blunt-end DNAfragments, African Jouralof Microbiology Research, 2011, 10:11149-11151

23. Wen ZZ,Wang YH, Yang B,Xie MQ,KC. Chou .Roles of L5-7 Loop in the Structure and ChaperoneFunction of SsHSP14.1, Protein and Peptide Letters, 2011, 18: 275-281

24. Qin XL,Wang YM,Wang YH,Huang HH,Yang B. Preparation and Characterization of 1,3-Dioleoyl-2-palmitoylglycerol. Journalof Agricultural and Food Chemistry, 2011, 59: 5714–5719